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Table 2 Results of univariate analysis: differences in demographics, vascular risk factors and clinical features in acute ischaemic stroke patients according to outcome

From: Pretreatment with statins improves early outcome in patients with first-ever ischaemic stroke: a pleiotropic effect of statins or a beneficial effect of hypercholesterolemia?

Data Vital status at discharge Favourable outcome (mRS grades 0-2)
  Alive Death Pvalue Yes No Pvalue
No. patients 1833 249   382 1700  
Male sex 882 (48.1) 105 (42.2) 0.045 195 (51.0) 792 (46.6) 0.064
Age, years, mean (SD) 80.7 (8.9) 74.2(12.4) 0.000 74.6 (10.9) 75 (12.5) 0.014
Age, years ≥ 85 years 330 (18) 94 (37.8) 0.000 56 (14.7) 368 (21.6) 0.001
Vascular risk factors       
   Hypertension 997 (54.4) 123 (49.4) 0.077 200 (52.4) 928 (54.6) 0.244
   Diabetes mellitus 421 (23) 50 (20.1) 0.174 93 (24.3) 78 (4.6) 0.142
   Valvular heart disease 111 (6.1) 19 (7.6) 0.202 28 (7.3) 102 (6) 0.195
   Ischaemic heart disease 168 (9.2) 57 (22.9) 0.001 50 (13.1) 269 (15.8) 0.102
   Atrial fibrillation 481 (26.2) 128 (51.4) 0.000 94 (24.6) 515 (30.3) 0.015
   Congestive heart failure 76 (4.1) 32 (12.9) 0.000 9 (2.4) 99 (5.8) 0.002
   Transient ischaemic attack 204 (11.1) 33 (13.2) 0.187 48 (12.6) 189 (11.1) 0.235
   Peripheral arterial disease 127 (6.9) 19 (7.6) 0.382 26 (6.8) 120 (7.1) 0.483
   Chronic pulmonary disease 132 (7.2) 34 (13.7) 0.001 21 (5.5) 145 (8.5) 0.027
   Obesity (BMI > 32.5 kg/m2) 97 (5.3) 6 (2.4) 0.060 24 (6.3) 79 (4.6) 0.116
   Alcohol abuse (> 80 g/day) 47 (2.6) 9 (3.6) 0.219 7 (1.8) 49 (2.9) 0.166
   Smoking (> 20 cigarettes/day) 193 (10.5) 14 (5.6) 0.013 32 (8.4) 175 (10.3) 0.149
Clinical features       
   Sudden onset 910 (49.6) 144 (57.8) 0.009 187 (49) 867 (51) 0.253
   Headache 242 (13.2) 17 (6.8) 0.002 47 (12.3) 212 (12.5) 0.504
   Dizziness 71 (3.9) 8 (3.2) 0.383 18 (4.7) 66 (3.9) 0.395
   Early seizures 23 (1.2) 14 (5.6) 0.000 4 (1.0) 33 (1.9) 0.163
   Nausea, vomiting 132 (7.2) 33 (13.2) 0.001 31 (8.1) 134 (7.9) 0.474
   Speech disturbances 925 (50.5) 147 (59.0) 0.007 200 (52.4) 872 (51.3) 0.375
   Altered consciousness 189 (10.3) 149 (59.8) 0.000 24 (6.3) 314 (18.5) 0.000
   Limb weakness 1334 (72.8) 232 (93.2) 0.000 259 (67.8) 1307 (76.9) 0.000
   Sensory symptoms 672 (36.7) 137 (55.0) 0.000 109 (28.5) 700 (41.2) 0.000
   Hemianopia 293 (16) 76 (30.5) 0.000 30 (7.9) 339 (19.9) 0.000
   Ataxia 122 (6.7) 7 (2.8) 0.008 25 (6.5) 104 (6.1) 0.414
   Cranial nerve palsy 85 (4.6) 16 (6.4) 0.122 14 (3.7) 87 (5.1) 0.143
Statin use before stroke 356 (19.5) 23 (9.2) 0.000 84 (22) 297 (17.5) 0.025
Hospital stay, days, median (25th-75th interquartile range) 12 (9-20) 10 (4.7-23) 0.000 10 (8-14) 13 (8-22) 0.000
  1. Percentages in parenthesis unless otherwise stated. Percentages are calculated for the total number in each column.