Skip to main content

Table 3 Rate ratios (RR) and 95% confidence intervals (CI) of mortality in 1131 amyotrophic lateral sclerosis cases according to smoking status, General Practice Research Database, 1990-2008

From: Association of smoking with amyotrophic lateral sclerosis risk and survival in men and women: a prospective study

Smoking status

N. deaths

Person-years

RR (95% CI) *

Entire sample

Never

266

722.7

1.00 (ref.)

Ever

394

1103.3

1.06 (0.90-1.23)

   Former

191

496.4

1.11 (0.92-1.34)

   Current

203

606.9

1.01 (0.84-1.21)

   Non-heavy smokers

352

1029.7

1.02 (0.87-1.20)

   Heavy smokers

42

73.6

1.45 (1.03-2.03)

Missing

142

530.8

0.92 (0.74-1.14)

Men

Never

141

400.9

1.00 (ref.)

Ever

213

733.4

0.90 (0.72-1.11)

   Former

106

347.4

0.91 (0.71-1.17)

   Current

107

386.0

0.88 (0.69-1.14)

   Non-heavy smokers

195

695.8

0.88 (0.71-1.10)

   Heavy smokers

18

37.6

1.08 (0.65-1.79)

Missing

76

282.8

0.91 (0.68-1.22)

Women

Never

125

321.9

1.00 (ref.)

Ever

181

369.9

1.31 (1.04-1.65)

   Former

85

149.0

1.46 (1.11-1.94)

   Current

96

220.9

1.20 (0.92-1.57)

   Non-heavy smokers

157

333.9

1.26 (0.99-1.59)

   Heavy smokers

24

36.0

1.94 (1.24-3.06)

Missing

66

248.0

0.92 (0.67-1.26)

  1. * Cox proportional hazards model adjusted for age, gender, diagnosis (ALS vs. ALS variant), and year of diagnosis.