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Table 1 MACPAF: Inclusion and exclusion criteria.

From: Stroke risk associated with balloon based catheter ablation for atrial fibrillation: Rationale and design of the MACPAF Study

Inclusion criteria:
• Patients with ECG-documented symptomatic paroxysmal atrial fibrillation
• At least one ineffective antiarrhythmic drug treatment
• Age ≥ 18 and ≤ 75 years
Exclusion criteria
• Previous ablation procedure for AF
• Cardiac surgery ≤ 3 months
• Left atrial diameter > 50 mm or ejection fraction < 35%
• Instable coronary artery disease or clinically relevant cardiac valve insufficiency
• Hyperthyroidism, pregnancy or lactation
• Coumadin or heparin intolerance
• Concomitant disease with expected lifespan < 2 years
• Contraindications for MRI
• Acute cerebral infarction (DWI lesion) detected by brain MRI before LACA