| |
BT PATIENTS (N = 73, 146 chromosomes)
|
CONTROLS (N = 220, 440 chromosomes)
|
OR (95% CI); P
|
|---|
|
GENOTYPES
| | | |
|
PON1 55 Leu/Leu
|
11 (15.1) [6.9-23.3]
|
38 (17.3) [12.3-22.3]
|
0.85 (0.41-1.75); 0.6621
|
|
PON1 55 Leu/Met
|
32 (43.8) [32.5-55.2]
|
94 (42.7) [36.2-49.3]
|
--
|
|
PON1 55 Met/Met
|
30 (41.1) [29.8-52.4]
|
88 (40.0) [33.5-46.5]
|
1.05 (0.61-1.79); 0.8692
|
|
PON1 192 Gln/Gln
|
31 (42.5) [31.1-53.8]
|
109 (49.5) [42.9-56.2]
|
0.75 (0.44-1.28); 0.2951
|
|
PON1 192 Gln/Arg
|
33 (45.2) [33.8-56.6]
|
89 (40.5) [34.0-46.9]
|
--
|
|
PON1 192 Arg/Arg
|
9 (12.3) [4.8-19.9]
|
22 (10.0) [6.0-14.0]
|
1.27 (0.57-2.85); 0.5762
|
|
ALLELES
| | | |
|
PON1 55 Leu
|
54 (37.0) [29.2-44.8]
|
170 (38.6) [34.1-43.2]
|
0.93 (0.63-1.37); 0.7223
|
|
PON1 55 Met
|
92 (63.0) [55.2-70.8]
|
270 (61.4) [56.8-65.9]
|
--
|
|
PON1 192 Gln
|
95 (65.1) [57.3-72.8]
|
307 (69.8) [65.5-74.1]
|
--
|
|
PON1 192 Arg
|
51 (34.9) [27.2-42.7]
|
133 (30.2) [25.9-34.5]
|
1.24 (0.84-1.84); 0.2893
|
- The values in each cell represent: number (percentage) and [95% confidence intervals]. 1The OR was calculated by using the dominant model. 2The OR was calculated by using the recessive model. 3The OR was calculated by using the allelic model. Test for trend with the number of variant alleles: PON1 55 Leu/Met: H = 0.0957 df = 1 p = 0.7570; PON1 192 Gln/Arg: H = 1.1416 df = 1 p = 0.2853.
