Skip to main content

Advertisement

Table 1 PON1 genotype and allelic variants of patients with brain tumor (BT) and healthy volunteers.

From: Two common nonsynonymous paraoxonase 1 (PON1) gene polymorphisms and brain astrocytoma and meningioma

  BT PATIENTS (N = 73, 146 chromosomes) CONTROLS (N = 220, 440 chromosomes) OR (95% CI); P
GENOTYPES    
PON1 55 Leu/Leu 11 (15.1) [6.9-23.3] 38 (17.3) [12.3-22.3] 0.85 (0.41-1.75); 0.6621
PON1 55 Leu/Met 32 (43.8) [32.5-55.2] 94 (42.7) [36.2-49.3] --
PON1 55 Met/Met 30 (41.1) [29.8-52.4] 88 (40.0) [33.5-46.5] 1.05 (0.61-1.79); 0.8692
PON1 192 Gln/Gln 31 (42.5) [31.1-53.8] 109 (49.5) [42.9-56.2] 0.75 (0.44-1.28); 0.2951
PON1 192 Gln/Arg 33 (45.2) [33.8-56.6] 89 (40.5) [34.0-46.9] --
PON1 192 Arg/Arg 9 (12.3) [4.8-19.9] 22 (10.0) [6.0-14.0] 1.27 (0.57-2.85); 0.5762
ALLELES    
PON1 55 Leu 54 (37.0) [29.2-44.8] 170 (38.6) [34.1-43.2] 0.93 (0.63-1.37); 0.7223
PON1 55 Met 92 (63.0) [55.2-70.8] 270 (61.4) [56.8-65.9] --
PON1 192 Gln 95 (65.1) [57.3-72.8] 307 (69.8) [65.5-74.1] --
PON1 192 Arg 51 (34.9) [27.2-42.7] 133 (30.2) [25.9-34.5] 1.24 (0.84-1.84); 0.2893
  1. The values in each cell represent: number (percentage) and [95% confidence intervals]. 1The OR was calculated by using the dominant model. 2The OR was calculated by using the recessive model. 3The OR was calculated by using the allelic model. Test for trend with the number of variant alleles: PON1 55 Leu/Met: H = 0.0957 df = 1 p = 0.7570; PON1 192 Gln/Arg: H = 1.1416 df = 1 p = 0.2853.
Back to article page