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Table 2 PON1 genotype and allelic variants of patients with different types of brain tumor.

From: Two common nonsynonymous paraoxonase 1 (PON1) gene polymorphisms and brain astrocytoma and meningioma

  Astrocytoma (N = 44, 88 chromosomes) OR (95% CI); P Meningioma (N = 29, 58 chromosomes) OR (95% CI); P
GENOTYPES     
PON1 55 Leu/Leu 8 (18.2) [6.8-29.6] 1.07 (0.47-2.43); 0.8851 3 (10.3) [0-21.4] 0.55 (0.17-1.81); 0.3451
PON1 55 Leu/Met 19 (43.2) [28.5-57.8] -- 13 (44.8) [26.7-62.9] --
PON1 55 Met/Met 17 (38.6) [24.2-53.0] 0.94 (0.49-1.82); 0.8662 13 (44.8) [26.7-62.9] 1.22 (0.57-2.62); 0.6192
PON1 192 Gln/Gln 19 (43.2) [28.5-57.8] 0.77 (0.41-1.48); 0.4421 12 (41.4) [23.5-59.3] 0.72 (0.33-1.56); 0.4091
PON1 192 Gln/Arg 20 (45.5) [30.7-60.2] -- 13 (44.8) [26.7-62.9] --
PON1 192 Arg/Arg 5 (11.4) [2.0-20.7] 1.15 (0.43-3.14); 0.7862 4 (13.8) [1.2-26.3] 1.44 (0.48-4.34); 0.5312
ALLELES     
PON1 55 Leu 35 (39.8) [29.5-50.0] 1.05 (0.66-1.67); 0.8423 19 (32.8) [20.7-44.8] 0.77 (0.44-1.38); 0.3863
PON1 55 Met 53 (60.2) [50.0-70.5] -- 39 (67.2) [55.2-79.3] --
PON1 192 Gln 58 (65.9) [56.0-75.8] -- 37 (63.8) [51.4-76.2] --
PON1 192 Arg 30 (34.1) [24.2-44.0] 1.19 (0.74-1.94); 0.4743 21 (36.2) [23.8-48.6] 1.31 (0.74-2.31); 0.3553
  1. The values in each cell represent: number (percentage) and [95% confidence intervals]. 1The OR was calculated by using the dominant model. 2The OR was calculated by using the recessive model. 3The OR was calculated by using the allelic model. Test for trend with the number of variant alleles: Astrocytoma PON1 55 Leu/Met: H = 0.0360 df = 1 p = 0.8496; PON1 192 Gln/Arg: H = 0.5537 df = 1 p = 0.4568. Meningioma PON1 55 Leu/Met: H = 0.5987 df = 1 p = 0.4391; PON1 192 Gln/Arg: H = 0.8057 df = 1 p = 0.3694.