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Table 2 Comparison between the mean of the MRC, HFMS and Barthel index scores in the first evaluation and the subsequent evaluations in the 22 SMA patients treated with VPA.

From: Evaluation of muscle strength and motor abilities in children with type II and III spinal muscle atrophy treated with valproic acid

Evaluation

MRC

HFMS

Barthel

1 × 2

-0.0 ± 0.4 (p = 0.999)

-0.8 ± 0.4 (p = 0.038)

-0.0 ± 0.7 (p = 0.999)

1 × 3

-0.1 ± 0.6 (p = 0.947)

-1.0 ± 0.5 (p = 0.056)

-1.3 ± 0.9 (p = 1.53)

1 × 4

-0.4 ± 0.7 (p = 0.600)

-1.4 ± 0.6 (p = 0.039)

-2.3 ± 1.1 (p = 0.043)

1 × 5

-1.0 ± 0.8 (p = 0.267)

-1.4 ± 0.7 (0.063)

-2.7 ± 1.3 (p = 0.045)