Figure 2
Alteration of the lesion size by different stroke subtypes. Scatter graphs of the ratios (T2WI/DWI) of edaravone(-) group (open circle) and edaravone(+) group (closed circle) in cardioembolism (A), large-artery atherosclerosis (C) and small-vessel occlusion (E) stroke subtypes. Average ratios of edaravone(-) group (white bar) and edaravone(+) group (black bar) in the cardioembolism (B), the large-artery atherosclerosis (D) and the small-vessel occlusion (F). Number of cases is indicated in the bar. The regression lines indicate in dotted line as edaravone(-) group and in black line as edaravone(+) group (the formula of cardioembolism: y = 1.07-0.14x, R2 = 0.53, p = 0.160 and y = 0.82-0.004x, R2 = 0.003, p = 0.786, respectively; the formula of large-artery atherosclerosis: y = 1.10-0.03x, R2 = 0.14, p = 0.028 and y = 0.81-0.01x, R2 = 0.03, p = 0.205, respectively; the formula of small-vessel occlusion: y = 1.18-0.32x, R2 = 0.14, p = 0.054 and y = 0.68-0.02x, R2 = 0.20, p = 0.007, respectively). In the small-vessel occlusion, the reduction of lesion size is earlier in edaravone(+) group compared with edaravone(-) group. There are significant differences of the average ratios between edaravone(-) and edaravone(+) groups in 1-2 months and 7-12 months in the small-vessel occlusion. *: p < 0.05 and **: p < 0.01.