Normalized pressure decline at the clot-filled carrier for two different thrombolysis experiments (each n = 5). Group A (black curves): Clots with an incubation time of 2 hours under a defined pulsatile flow condition. Group B (red curves): Clots with an incubation time of 1 hour under the same pulsatile flow condition undergoing sonothrombolysis (combined treatment with ultrasound and the thrombolytic agent rt-PA) between t = 60 and 120 minutes. Solid lines: Starting point normalized, error adjusted mean values. Dashed lines: Standard errors.