| Control n = 90 | Early intervention n = 129 | P value | Odds ratio (95% CI) |
---|---|---|---|---|
Primary Outcome, n (%) | Â | Â | Â | Â |
Death | 7 (7.8) | 2 (1.6) | 0.034 | 0.19 (0.04-0.92) |
FOIS 1 | 17 (18.9) | 8 (6.2) | Â | Â |
FOIS 2, 3 | 5 (5.6) | 7 (5.4) | Â | Â |
FOIS 4-6 FOIS 7 | 46 (51.1) 15 (16.7) | 74 (57.4) 38 (29.5) | 0.001 | 3.13 (1.60-6.15) |
Secondary Outcome | Â | Â | Â | Â |
   Infection, n (%) |  |  |  |  |
Any infection | 36 (40.0) | 43 (33.3) | 0.312 | 0.75 (0.43-1.31) |
Chest infection | 32 (35.6) | 27 (20.9) | 0.016 | 0.48 (0.26-0.88) |
   Antibacterial drugs, vial/patient (SD) | 16.3 (39.6) | 6.1 (15.6) | 0.009 |  |
   Length of hospital stay, days (SD) | 44.2 (27.2) | 31.9 (19.8) | < 0.001 |  |
   Functional outcome, n (%) |  |  |  |  |
(favorable) | Â | Â | Â | Â |
mRS 0-2 | 17 (18.9) | 31 (24.0) | 0.366 | 1.36 (0.70-2.64) |
GOS 4-5 | 18 (20.0) | 42 (32.6) | 0.040 | 1.93 (1.02-3.64) |
(unfavorable) | Â | Â | Â | Â |
mRS 5-6 | 48 (53.3) | 51 (39.5) | 0.044 | 0.57 (0.33-0.99) |
GOS 1-2 | 19 (21.1) | 7 (5.4) | < 0.001 | 0.21 (0.09-0.54) |