Table 3 Correlations of cognitive and MSFC measures with physical and mental MSQOL-54 and EDSS at screening (Day 0) and Month 24

Power of Attention

0.14

p = 0.4371

0.21

p = 0.2707

0.1

p = 0.5311

0.07

p = 0.6964

0.62

p < 0.0001

0.5

p = 0.0023

Continuity of Attention

0.16

p = 0.2395

0.34

p = 0.0755

0.04

p = 0.8276

0.04

p = 0.8132

0.43

p = 0.0062

0.53

p = 0.001

Quality of working Memory

0.06

p = 0.733

0.35

p = 0.0598

0.14

p = 0.3742

0.41

p = 0.017

0.48

p = 0.0018

0.37

p = 0.0276

Quality of Episodic Memory

0.01

p = 0.9654

0.64

p = 0.0034

0.02

p = 0.9028

0.6

p = 0.0029

0.33

p = 0.0422

0.35

p = 0.0892

Speed of Memory

0.18

p = 0.3038

0.42

p = 0.0239

0.02

p = 0.8819

0.19

p = 0.2949

0.45

p = 0.0035

0.43

p = 0.0092

CDR composite

0.19

p = 0.2711

0.47

p = 0.0412

0.13

p = 0.4107

0.25

p = 0.2676

0.59

p < 0.0001

0.61

p = 0.0015

DSST

0.24

p = 0.1618

0.27

p = 0.2395

0.09

p = 0.5748

0.06

p = 0.7577

0.47

p = 0.0028

0.76

p < 0.0001

Timed 25-FWT

0.35

p = 0.0373

0.27

p = 0.154

0.15

p = 0.343

0.07

p = 0.6786

0.0

p = 0.9764

0.49

p = 0.002

9-HPT

0.0

p = 0.9896

0.08

p = 0.6629

0.23

p = 0.12

0.08

p = 0.652

0.55

p = 0.0001

0.53

p = 0.0003

PASAT 3"

0.03

p = 0.8805

0.16

p = 0.411

0.07

p = 0.6612

0.06

p = 0.7142

0.4

p = 0.0071

0.42

p = 0.0091

MSFC

0.17

p = 0.3352

0.19

p = 0.3328

0.02

p = 0.9241

0.12

p = 0.4834

0.43

p = 0.0044

0.56

p = 0.0003