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Table 1 Demographics and clinical data

From: Enhanced catecholamine transporter binding in the locus coeruleus of patients with early Parkinson disease

  PD HC
Subjects N. (male/female) 94 (67/27) 15 (4/11)*
Age at SPECT 60 (38 - 75) 63 (51 - 74)
Age at motor symptoms onset 57 (37 - 72)  
Disease duration 3 (1 - 5)  
UPDRS motor score (part-III) [range 0 - 108] 19 (8 - 56)  
Hoehn and Yahr stage [range 1 - 5] 2 (1 - 2)  
L-Dopa in mg/day 400 (0 - 850)  
LEDDs in mg/day 250 (70 - 1200)  
  1. Data are reported as median and range (brackets). Age at SPECT, age at motor symptoms onset and disease duration are in years. All patients were evaluated with the Unified Parkinson Disease Rating Scale motor part (UPDRS part III) in drugs-off state (i.e. after overnight withdrawal of specific drugs for PD, no patients was taking long-acting dopaminergic drugs). LEDDs were calculated as follow: 100 mg levodopa = 1.5 mg pramipexole = 6 mg ropinirole. * p = 0.0005.