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Table 1 Characteristics of healthy subjects and patients with MS

From: Decreased CD8+T cell response to Epstein-Barr virus infected B cells in multiple sclerosis is not due to decreased HLA class I expression on B cells or monocytes

 

HC

(n= 59)

All MS

(n= 62)

RRMS

(n= 23)

SPMS

(n= 25)

PPMS

(n= 14)

Age (years)

40.4 ± 10.8

45.5 ± 12.1

38.0 ± 9.7

50.8 ± 10.1

48.2 ± 13.3

Sex (% female)

67.8

69.3

73.9

68.0

64.3

Age of onset of MS (years)

 

33.5 ± 9.6

31.4 ± 10.6

33.4 ± 8.3

36.9 ± 9.7

Duration of MS (years)

 

12.8 ± 8.4

7.6 ± 6.5

18.0 ± 7.7

11.9 ± 7.1

EDSS score

 

5.1 ± 2.3

3.1 ± 1.8

6.3 ± 1.9

6.1 ± 1.6

MSSS

 

6.2 ± 2.6

4.9 ± 2.8

6.9 ± 2.4

7.4 ± 1.9

  1. All values except for sex presented as mean ± standard deviation.
  2. HC: healthy control subjects, All MS: total group of MS patients, RRMS: relapsing-remitting MS, SPMS: secondary progressive MS, PPMS: primary progressive MS, EDSS: Expanded Disability Status Scale, MSSS: MS Severity Score.