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Table 1 Demographics and Standardized Neuropsychological Tests for the 4 Groups [ mean (standard deviation)]

From: Memory and Executive Screening (MES): a brief cognitive test for detecting mild cognitive impairment

Index

NC (n=197)

aMCI-sd (n=116)

aMCI-md (n=195)

AD (n=228)

F(P)

Age

68.84 (7.70)

70.04 (9.13)

70.27 (8.75)

70.19 (9.17)

1.164 (0.323)

Education

9.42 (5.17)

9.66 (4.85)

9.14 (5.19)

9.21 (4.98)

0.313 (0.816)

Sex1

110:89

53:63

96:100

129:102

1.813 (0.143)

MMSE

27.05 (2.11)

25.59 (2.61) **

25.17 (2.72) $$

19.09 (2.58)##

414.451 (<0.001)

AVLT-delayed recall(M=12)

5.30 (2.01)

1.19 (1.31) ††**

1.01 (1.27)

0.27 (0.83)##

176.26 7(<0.001)

BNT(M=30)

23.56 (4.55)

23.56(4.75) ††

21.08 (3.51) $$

18.01 (5.47)##

21.787 (<0.001)

SDMT

41.40 (11.98)

37.40 (10.57) ††

29.37 (13.48) $$

20.16 (11.89)##

33.441 (<0.001)

CFT-Copy(M=36)

33.22 (3.42)

32.86 (3.13) †

29.73 (7.54) $

24.74 (9.31)##

22.917(<0.001)

CFT-delayed recall(M=36)

15.47 (5.55)

11.69 (7.39) †

9.07 (5.58) $$

4.15 (3.34) ##

38.909(<0.001)

CWT-CR(M=50)

45.73 (3.94)

42.96 (9.61) †

38.70 (10.43) $$

29.50 (13.68)##

33.370(<0.001)

TMT-partA(s)

55.08 (20.78)

64.43 (25.25) ††

84.66 (36.57) $$

118.30 (48.31) ##

36.214(<0.001)

TMT-part B(s)

155.89 (63.99)

172.08 (68.55)††

250.37(107.90)$$

331.28(131.65)##

32.921(<0.001)

CESD

11.43(2.24)

13.67(3.12)

10.30(2.79)

10.64(3.06)

1.329(0.266)

  1. Comparison between NC group and aMCI-sd group is marked behind ‘aMCI-sd group’; ** P<0.01.
  2. Comparison between aMCI-sd group and aMCI-md group is marked behind ‘aMCI-sd group’; † P<0.05; †† P<0.01.
  3. Comparison between aMCI-md group and AD group is marked behind ‘aMCI-md group’; $ P<0.05; $$ P<0.01.
  4. Comparison between NC group and AD group is marked behind ‘AD group’. # P<0.05; ## P<0.01.
  5. AVLT: Auditory Verbal Learning Test; BNT: Boston Naming Test; SDMT: Symbol Digit Modalities Test; CFT: Rey-Osterrieth Complex Figure Test; CWT-CR: Card C right of Stroop Color-Word Test; TMT: Trail Making Test; CESD: Center for Epidemiologic Studies Depression.
  6. 1 chi-square test, M=maximum.