Table 3 Outcome Measures: white matter lesion quantification
Reference | Sequence | WML Location | MRI Magnet |
|---|---|---|---|
WML Type | WML Quantification | ||
Groot et al. [24] | PD, T1, T2 | S: Four lobes of Frontal, Parietal, Occipital, and Temporal | 1.5 T |
P, S, Regions | Scoring | P: Adjacent frontal horns, lateral ventricles wall, and occipital horns | |
Shenkin et al. [25] | T2, FLAIR | - | 1.5 T |
S, P | Scoring | ||
Baune et al. [26] | PD, T1, T2 | - | 1.5 T |
S, P | Scoring | ||
Kim et al. [27] | T2, FLAIR | - | 1.5 T |
S, P | Volum | ||
Silbert et al. [28] | PD, T2 | - | 1.5 T |
S, P | Volume | ||
McClleland et al. [21] | PD, T1, T2 | Cerebral White Matter, Cerebellar White Matter, Basal Ganglia | 1.5 T |
Regions | Scoring | ||
Wright et al. [29] | PD, T2, FLAIR | Frontal, Deep, and Occipital-Temporal-Parietal | 1.5 T |
S, I, Regions | Volume | ||
Kaplan et al. [30] | T2, FLAIR | Frontal and Posterior Regions | 3.0 T |
Regions | Volume | ||
Wakefield et al. [31] | T1, FLAIR | Anterior, Superior, Posterior Corona Radiata | 3.0 T |
Regions | Volume | Cingulate Gyrus, Genu, Body, Splenium of Corpus Callusum | |
Anterior and Posterior Limb of Internal Capsule | |||
Superior Longitudinal Fasciculus | |||
O’Brien et al. [32] | T2, FLAIR | Internal and External Capsule | 1.5 T |
Regions | Scoring | ||
Smith et al. [14] | PD, T1, T2 | Whole Brain | 1.5 T |
Regions | Volume | ||
Burns et al. [33] | T1, T2 | S: Frontal, Parietal, Temporal, and Occipital Lobes | 1.5 T |
S, P, Regions | Scoring | P: Right and Left Frontal Horns, Posterior Horns, and Ventricular Bodies | |
Ishii et al. [34] | T2 | S: Left and Right | 1.5 T |
P, S, Regions | Scoring | P: Anterior and Posterior | |
Tullberg et al. [35] | T1, T2 | Orbitofrontal, Prefrontal, Dorsolateral Frontal, Parietal, and Occipitotemporal | 1.5 T |
Regions | Volume | Â | Â |