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Table 1 Participant characteristics

From: An olfactory ‘stress test’ may detect preclinical Alzheimer’s disease

 

NCn= 29

CIn= 13

ADn= 14

Significancen= 56

Age

74.0 (6.6)

77.1 (5.6)

75.3 (4.6)

F(2,53) = 1.3, P = 0.28

Female n, (%)

20 (69)

7 (54)

4 (29)

χ(2) 2 =6.2, P = 0.04

Education y (SD)

10.6 (3.1)

11.3 (3.3)

11.1 (2.6)

F(2,53) = 0.33, P = 0.77

MMSE (SD)

29.0 (1.6)

27.6 (2.4)

23.6 (4.0)

F(2,53) = 21.0, P < 0.001, NC, CI > AD

ARCSg

107.2 (9.3)

84.7 (10.8)

57.2 (21.1)

F(2,53) = 66.2,P < 0.001, NC > CI > AD

Mem

104.0 (11.5)

72.1 (19.9)

60.4 (12.9)

F(2,53) = 52.7,P < 0.001, NC > CI, AD

UPSIT_20

14.3 (2.6)

14.6 (2.9)

10.4 (2.7)

F(2,53) = 11.5, P < 0.001, NC, CI > AD

AE

0.28 (2.15)

−2.77 (2.71)

−2.43 (1.45)

F(2,53) = 12.5, P < 0.001, NC > CI, AD

LHCV

1819 (370)

1410 (363)

1385 (293)

F(2,48) = 9.1, P < 0.001, NC > CI, AD

  1. Numbers shown represent mean (SD). NC: Normal Control; CI: Cognitive Impairment; AD: Alzheimer’s Disease; ARCSg: Scaled global score on the Audio Recorded Cognitive Screen (ARCS); Mem: Scaled memory domain score on the ARCS; UPSIT_20: Score on 20 items of the 40 item University of Pennsylvania Smell Identification Test; AE: Atropine Effect; LHCV: Left hippocampal volume adjusted for intracranial volume (cubic mm).