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Table 2 Pearson correlations between baseline UPSIT, AE, LHCV and APOE and cognitive test scores

From: An olfactory ‘stress test’ may detect preclinical Alzheimer’s disease

 

All participantsn= 56

 

UP_20

APOE

LHCV

MMSE

ARCSg

Mem

Flu

Lang

VS

Atten

UPSIT_20

1

−0.04

0.17

0.43**

0.41**

0.39**

0.15

0.19

0.46**

0.40**

AE

0.06

−0.33*

0.53**

0.37**

0.51**

0.57**

0.36**

0.38**

0.28*

0.31*

LHCV

0.17

−0.12

1

0.45**

0.56**

0.57**

0.34*

0.40**

0.43**

0.28*

 

Non – Demented n = 42

UPSIT_20

1

−0.05

0.12

0.33*

0.12

0.11

−0.10

−0.02

0.25

0.17

AE

−0.15

−0.30

0.49**

0.22

0.50**

0.52**

0.31*

0.29

−0.02

0.21

LHCV

0.12

−0.08

1

0.29

0.44**

0.47**

0.14

0.23

0.23

0.15

 

AD n = 14

UPSIT_20

1

0.28

−0.53

−0.17

−0.31

−0.04

−0.42

−0.34

−0.07

0.18

AE

−0.05

−0.41

0.52

0.50

0.48

0.47

0.16

0.38

0.46

−0.03

LHCV

−0.53

−0.16

1

0.58*

0.80**

0.71**

0.48

0.54

0.59*

0.10

  1. * P < 0.05; ** P < 0.01; UP_20: Score on 20 items of the 40 item University of Pennsylvania Smell Identification Test (UPSIT_20); AE: Atropine Effect; LHCV: Left hippocampal volume adjusted for intracranial volume; APOE: Apolipoprotein E allele dichotomised (no ϵ4 = 0, any ϵ4 = 1); MMSE: Mini Mental State Examination; ARCSg: Scaled global score on the Audio Recorded Cognitive Screen (ARCS); Mem: Scaled memory domain score on the ARCS; Flu: Scaled fluency domain score on the ARCS; Lang: Scaled language domain score on the ARCS; VS: Scaled visuospatial domain score on the ARCS; Atten: Scaled attention/executive domain score on the ARCS.
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BMC Neurology

ISSN: 1471-2377

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