Reference | Tulder | LOE | Design | Patients | Interv CG | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | int val | descr | stat | total |  |  | MS type | EDSS | Age | TSFS | TSLE at least | EG (n) | CG (n) |  |
Gehlsen et al. [24] | 2 | 3 | 2 | 7 | C | CS | ? | ? | 40.2 | ? | ? | 10 | no | Â |
5 | 6 | 2 | 13 | B | RCT | ? | 1-5.5 | 44 (7.1) | 6 (0–23) | 1 mo | 47 | 48 | no | |
Taylor al. [25] | 5 | 4 | 2 | 11 | C | CS | ? | 0-6.5 | 45.6 (27–61) | 6 (1–13)* | 1 mo | 12 | no |  |
Freeman et al. [26] | 4 | 4 | 2 | 10 | B | RCT | SP,PP | 5-9.5 | 43 (25–73) | 15.4 (3–32) | 1 mo | 32 | 34 | WL |
Khan et al. [33] | 9 | 5 | 2 | 16 | A2 | RCT | RR, SP,PP | 0-8 | 49.5 (30–63) | 10.7 (6.3)* | 3 mo | 48 | 50 | WL (maint) |
Mark et al. [27] | 3 | 4 | 2 | 9 | C | Pilot | PP, SP | 6-7 | 56 (50–60) | ? | 3 mo | 5 | no |  |
Patti et al. [28] | 7 | 6 | 2 | 15 | A2 | RCT | SP,PP | 4-8 | 25-60 | 1.5 (0.5-2.5) | 3 mo | 58 | 53 | home exerc. |
Jones et al. [29] | 2 | 4 | 1 | 7 | B | CCT | moderate to severe ataxia and PP, SP | ? | 36.9 (8.2) | ? | 1 year | 28 | 9 | WL |
Mathiowetz et al. [30] | 3 | 4 | 2 | 9 | C | CS | B, RR,PP, SP | 2.5-8 | 45 (27–63) | 12 (1–27) | ? | 30 | no |  |
Storr et al. [31] | 6 | 4 | 2 | 12 | B | RCT | P, S, RR | 0-9 | 53 (33–66) | 15 (3–45) | 3 mo | 38 | 52 | WL |
Vikman et al. [32] | 4 | 4 | 2 | 10 | C | CS/CCT** | RR,SP,PP | 4-6.5 | 55.8 (10.3) | 18.3 (2–43) | ? | 40 + 18 | 18 | WL |