Figure 4

The effects of levosimendan on the extracellular concentrations of lactate [A], glucose [B], pyruvate [C], glutamate [D] and the lactate/pyruvate ratio [E] during 15 min of bilateral cerebral ischaemia/hypoxia and 90 min of reperfusion. The amount of glutamate release and uptake was quantified by the area under the curve from plot D (The p-values indicate differences between the control and levosimendan from an ANOVA; * p < 0.05 vs. control, # p < 0.05 vs. sham).