Skip to main content

Table 2 The proportions of clinical radiological variables by the severity of obesity

From: Paradoxical effect of obesity on hemorrhagic transformation after acute ischemic stroke

  Underweight Normal weight Overweight Obesity I Obesity II Pfor trend*
  (< 18.5 kg/m2) (18.5-22.9 kg/m2) (23.0-24.9 kg/m2) (25.0-29.9 kg/m2) (≥ 30 kg/m2)  
Variables (n = 365) n = 18 (4.9%) n = 107 (29.3%) n = 94 (25.8%) n = 134 (36.7%) n = 12 (3.3%)  
Demographic       
  Age, y 71.1 ± 11.2 65.3 ± 12.7 65.2 ± 11.8 63.4 ± 11.1 61.0 ± 12.8 0.08
  Gender, male 15 (83.3%) 73 (68.2%) 62 (66.0%) 88 (65.7%) 8 (66.7%) 0.67
Clinical       
  Hypertension† 7 (38.9%) 50 (46.7%) 58 (61.7%) 96 (71.6%) 8 (66.7%) < 0.01
  Diabetes 3 (16.7%) 29 (27.1%) 32 (34.0%) 44 (32.8%) 2 (16.7%) 0.38
  Hyperlipidemia 1 (5.6%) 13 (12.1%) 17 (18.1%) 20 (14.9%) 1 (8.3%) 0.55
  Current smoking 7 (38.9%) 21 (19.6%) 23 (24.5%) 23 (17.2%) 2 (16.7%) 0.23
  Initial NIHSS score† 5 (3–12) 5 (2–11) 4 (2–9) 3 (2–5) 3 (1–6) < 0.01
  Thrombolysis 0 (0%) 9 (8.4%) 6 (6.4%) 9 (6.7%) 0 (0%) 0.61
  Acute heparin treatment 9 (50%) 37 (34.6%) 31 (33%) 39 (29.1%) 3 (25%) 0.44
  Antiplatelet Use 0 5 (4.7%) 4 (4.3%) 2 (1.5%) 0 0.48
  Warfarin Use 0 2 (1.9%) 5 (5.3%) 4 (3.0%) 0 0.54
Radiological       
  Hemorrhagic transformation† 4 (22.2%) 26 (24.3%) 14 (14.9%) 14 (10.4%) 1 (8.3%) 0.04
  Advanced WMLs 6 (35.3%) 26 (25%) 24 (26.1%) 35 (26.3%) 1 (8.3%) 0.6
  Presence of microbleeds 2 (11.8%) 20 (19.4%) 21 (22.8%) 36 (27.1%) 4 (33.3%) 0.42
  1. Values are mean ± SD, median (interquartile range), or number of participants (percentage).
  2. NIHSS indicates National Institute of Health Stroke Scale; WMLs, white matter lesion.
  3. *Based on χ2 test of trend across the severity of obesity.
  4. P < 0.05.