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Table 3 Immune-mediated encephalitis

From: Autoimmune causes of encephalitis syndrome in Thailand: prospective study of 103 patients

Clinical course & investigations

NMDA

Demyelinating diseases/NMO

AMPA

Behcet

ANNA2 (anti-Ri)

GABA

NMDA+ANNA2

VGKC

Anti-Yo

NPLE

Encephalitis: myelitis

4: 1

1: 2

0: 1

0: 1

5: 1

1: 0

1: 0

1: 0

2: 0

3: 1

Average age (yr)

39

52

2

33

67

70

18

67

16

31

(5–43)

(8–56)

(25–82)

 

(11–21)

(23–50)

Female: male

4: 1

3: 0

1: 0

2: 0

3: 3

0: 1

0: 1

0: 1

1: 1

4: 0

Underlying disease

ovarian teratoma (1)

-

-

-

DM(1), SLE(1) Ovarian cancer (1)

alcoholic cirrhosis

hemophagocytic syndrome

DM

Germ cells tumor (1)

SLE (4)

Prodrome symptoms

headache (2), fever (1)

fever (1)

fever with rash

-

fever (2), URI (1),

-

fever

fever + headache

fever (1), headache (1)

fever (2), weight loss (1), fatigue + rash + alopecia (1)

anorexia (1)

Presenting symptoms

psychosis + seizure (3), behavior change (1), quadripa resis (1)

behavior change ± Seizure (2), drowsy (1) parkinsonism (1)

stiff person

para paresis

psychosis ± seizure (2), Seizure (3), para paresis (1)

behavior change + Seizure (1)

seizure (1)

behavior change + Seizure (1)

behavior change (1), seizure (1)

behavior change (1), psychosis (1), seizure (1), paraparesis (1)

Average

          

CSF wbc

32

5

0

157

1

0

0

0

30

0

(cells/mm3)

(0–62)

(5–60)

  

(0–19)

   

(0–60)

(0–1)

Average CSF protein

30

45

22

55

40

36

58

51

43

99

(mg/dl)

(19–242)

(30–66)

(2–68)

(42–45)

(28–142)

Average CSF sugar (mg/dl)

62

73

59

40

83

71

53

149

70

65

(44–102)

(27–104)

(50–95)

(67–73)

(47–82)

Imaging pattern

normal (1), meninges (1), multifocal (2)

white matter (1), brainstem + midline (1)

normal

myelo pathy

non-specific change (2), temporal lobe (2), multiple cortical lesions (1)

white matter (1)

cerebral atrophy(1)

meninges + cortex (1)

non-specific white matter change (1), miscellenous (1)

midline + cortex (1), non-specific white matter change (1)

Outcome

complete recovered (1), partially recovered

partially recovered (1), disable (2)

partially recovered,

disable

partially recovered (4), Disable (3)

dead

partially recovered

partially recovered

partially recovered (2)

partially recovered (1), disable (2), dead (1)

 

(1), disable (3)

        Â