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Table 2 Demographic, clinical and Doppler sonography characteristics in multiple sclerosis patients in the PREMiSe study

From: Multimodal noninvasive and invasive imaging of extracranial venous abnormalities indicative of CCSVI: Results of the PREMiSe pilot study

 

Phase 2 (n = 20)

Female gender, n (%)

14 (70)

Age in years, mean (SD) median

44.3 (9) 44.6

Age at onset in years, mean (SD) median

33.4 (10) 35.5

Disease duration in years, mean (SD) median

10.9 (7.1) 10

Disease course, n (%)

 

  RR

13 (65)

  RP

7 (35)

EDSS, mean (SD) median

3.9 (1.5) 3.8

Type of treatment, n (%)

 

  Interferon beta

15 (75)

  Glatiramer acetate

4 (20)

  Combination

0 (0)

  Others

1 (5)

VH CCSVI criterion, n (%)

 

  VH1

8 (40)

  VH2

19 (95)

  VH3

20 (100)

  VH4

14 (70)

  VH5

4 (20)

≥2 CCSVI criteria*, n (%)

20 (100)

≥2 CCSVI extracranial criteria, n (%)

20 (100)

  1. Legend: PREMiSe - Prospective Randomized Endovascular therapy in Multiple Sclerosis (study); RR - relapsing-remitting; RP - relapsing-progressive; EDSS - Expanded Disability Status Scale; VH – venous hemodynamic; CCSVI -chronic cerebrospinal venous insufficiency; SD - standard deviation.
  2. *The overall CCSVI criteria report both the extracranial and intracranial assessments on DS.