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Table 4 Comparison of magnetic resonance venography (as "gold standard-benchmark") for the detection of abnormal findings in the internal jugular veins and in azygos vein/vertebral veins using other noninvasive and invasive imaging techniques

From: Multimodal noninvasive and invasive imaging of extracranial venous abnormalities indicative of CCSVI: Results of the PREMiSe pilot study

MRV

# of positive cases

Noninvasive and invasive imaging modalities

# of positive cases

Total # of cases

Sensitivity

Specificity

PPV

NPV

OR

IJV right

7

CV IJV right

11

20

35

53.8

45.5

77.8

2.92 (.41-20.89)

IVUS IJV right

10

71.4

34.8

25

80

4 (.55-29.09)

CV + IVUS IJV right

13

71.4

38.5

38.5

71.4

1.56 (.22-11.37)

IJV left

7

CV IJV left

14

19

57.1

23.1

28.6

50

.40 (.06-2.89)

IVUS IJV left

15

18

100

27.3

46.7

100

1.88 (1.17-3.01)

CV + IVUS IJV left

18

18

NA*

NA*

NA*

NA*

NA*

IJVs total

8

CV IJV total

17

20

75

8.3

35.3

33.3

.27 (.02-3.67)

IVUS IJV total

18

100

16.7

44.4

100

1.8 (1.19-2.72)

CV + IVUS IJV total

20

100

0

0.4

---

---

VVs total

3

CV azygos total

10

20

0

41.2

0

70

.7 (.47-1.05)

IVUS azygos total

17

100

17.6

17.6

100

1.21 (.97-1.51)

  

CV + IVUS azygos total

18

 

100

11.8

16.7

100

1.20 (.98-1.48)

  1. Legend: MRV - magnetic resonance venography; IJVs - internal jugular veins; VVs - vertebral veins; DS - Doppler sonography: MRV - magnetic resonance venography; CV - catheter venography; IVUS - intravascular ultrasound; OR - odds ratio.
  2. Nineteen and 18 patients successfully obtained CV and IVUS in the left IJV, respectively (because of difficulty to access with the wire). All 20 patients successfully obtained other noninvasive and invasive examinations in the explored vein territories. Therefore, for the left IJVs comparisons with CV and IVUS, only data from 19 and 18 patients were used.
  3. *The SPSS does not provide an estimate of odds ratio or its confidence interval whenever there is a zero count in the contingency table. Instead, it returns an estimate of relative risk.
  4. Therefore those results are reported as "not available".