Table 2 Demographic and clinical characteristics of study cohort grouped by JVR status (i.e. positive or negative) for all groups aggregated together
Variable | JVR negative | JVR positive | Significance p value |
|---|---|---|---|
Number of subjects, n (%) | 23 (34.3) | 44 (65.7) | n.a. |
Female gender, n (%) | 9 (39.1) | 16 (36.4) | 0.824* |
Age in years, mean (SD) | 81.6 (3.3) | 81.5 (6.2) | 0.740 |
Years of education, mean (SD) | 11.8 (3.8) | 11.5 (3.7) | 0.720 |
Disease classification, n (%) | 0.106* | ||
Control | 5 (21.7) | 13 (29.5) | |
MCI | 9 (39.1) | 24 (54.5) | |
AD | 9 (39.1) | 7 (15.9) | |
MMSE, mean (SD) | 24.0 (4.1) | 26.0 (3.1) | 0.065 |
Hypertension, n (%) | 12 (52.2) | 28 (63.6) | 0.364* |
Diabetes, n (%) | 6 (26.1) | 6 (13.6) | 0.207* |
Hyperlipidemia, n (%) | 5 (21.7) | 8 (18.2) | 0.727* |
Smoking, n (%) | 0 (0.0) | 2 (4.5) | 0.299* |
Normalized WB volume, mean (SD) | 1286.6 (58.3) | 1327.9 (54.8) | 0.014 |
Normalized GM volume, mean (SD) | 692.6 (41.0) | 726.1 (40.0) | 0.002 |
Normalized WM volume, mean (SD) | 594.0 (32.6) | 601.8 (32.5) | 0.531 |
CSF volume | 380.5 (58.7) | 362.0 (60.9) | 0.253 |