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Table 1 Eligibility criteria

From: The SCIentinel study - prospective multicenter study to define the spinal cord injury-induced immune depression syndrome (SCI-IDS) - study protocol and interim feasibility data

Inclusion criteria
(1) Patients with acute isolated spinal cord injury (AIS A-D) planned for surgical stabilization and decompression, lesion may include more than 1 segment
(2) Patients with acute isolated spinal fracture planned for surgical stabilization, lesion may include more than 1 segment
(3) ≥ 2 spinal cord or vertebral lesions definable one from another
(4) Legal age of the patient
(5) Documented informed consent of the patient
Exclusion criteria
(1) Non-traumatic spinal cord injury
(2) 2 or more spinal cord or vertebral lesions definable one from another
(3) Severe polytrauma (definition: patients with severe injuries of life-sustaining organ systems, which per se and in the acute phase are life-threatening (e.g., severe pelvic trauma, severe body cavity injuries)
(4) Concomitant traumatic brain injury (TBI) (definition: i) Patients with persisting neurological deficit in consequence of the TBI, ii) patient with severe TBI (Glasgow Coma Scale ≤ 8), and iii) patients with intracranial pressure monitoring sensors.)
(5) Neoplasia and/or antineoplastic therapy
(6) Rheumatic disease, collagenosis, vasculitis or other autoimmune disease
(7) Preexisting chronic infectious disease (before the injury)
(8) Preexisting systemic steroid treatment
(9) Severe alcohol or drug addiction
(10) Pregnancy, lactation