Table 1 Characteristic of serological studies
From: Chlamydia pneumoniae infection and cerebrovascular disease: a systematic review and meta-analysis
Author Y | Country | Study design | Number of case/control | Case assessment or endpoint | Serologic testing assay | Laboratory test/Marker | Adjustment |
|---|---|---|---|---|---|---|---|
Bandaru VC 2012 | India | CSCC | 100/100 | Ischemic stroke | MIF | IgA, IgG | Age, gender, diabetes, smoking, hypercholesterolemia, hyperhomocysteinemia. |
Hasan ZN 2011 | Iraq | CSCC | 50/40 | Ischemic stroke | ELISA | IgA, IgG | None |
Kēnina V 2011 | Latvija | CSCC | 102/48 | Ischemic stroke | ELISA | IgG | None |
Chen YJ 2010 | China | CSCC | 50/50 | Ischemic stroke | MIF | IgG | None |
Bandaru VC 2009 | India | CSCC | 120/120 | Ischemic stroke | MIF | IgA, IgG | None |
Bandaru VC 2009 | India | CSCC | 120/120 | Ischemic stroke | MIF | IgA, IgG | None |
Tiszlavicz Z 2009 | Hungary | CSCC | 280/150 | Ischemic stroke | ELISA | IgG | None |
Alavi SM 2009 | Iran | CSCC | 45/45 | Ischemic stroke | ELISA | IgG | None |
Bandaru VC 2008 | India | CSCC | 200/200 | Ischemic stroke | MIF | IgA, IgG | Age, diabetes, smoking, alcoholics, hypertension, hyperhomocystenemia, hypercholestemia. |
Lin TM 2008 | China | CSCC | 450/450 | Ischemic stroke | MIF | IgG | Gender, hypertension, diabetes, hypercholesterolemia, and smoking. |
Hu J 2008 | China | CSCC | 100/60 | Ischemic stroke, TIA | ELISA | IgG | None |
Kis Z 2007 | Hungary | CSCC | 59/52 | Ischemic stroke | ELISA | IgA, IgG | Age, gender |
Alamowitch S 2007 | France | CSCC | 483/483 | Ischemic stroke | MIF | IgA, IgG | Diabetes, smoking, hypertension, total cholesterol, CHD, season of enrolment. |
Piechowski JB 2007 | Poland | CSCC | 94/103 | Ischemic stroke | ELISA | IgA, IgG | Age and gender |
Chi LQ 2007 | China | CSCC | 50/48 | Ischemic stroke | ELISA | IgG | None |
Liu JX 2006 | China | CSCC | 47/48 | Ischemic stroke | ELISA | IgG | None |
Njamnshi AK 2006 | Cameroon | CSCC | 64/64 | Ischemic stroke, TIA | MIF | IgA, IgG | Diabetes, smoking, hypertension, obesity and alcohol intake. |
Elkind MS 2006 | USA | CSCC | 239/428 | Ischemic stroke | MIF | IgA, IgG | Age, gender, diabetes, smoking, atrial fibrillation, hypertension, HDL, LDL and race. |
Chen L 2006 | China | CSCC | 135/135 | Ischemic stroke | ELISA | IgG | None |
Liu AM 2006 | China | CSCC | 80/80 | Stroke | MIF | IgA, IgG | None |
Zhou B 2005 | China | CSCC | 76/80 | Ischemic stroke | EIA | IgA | Age, gender, smoking, alcohol intake, body weight, hypertension, cholesterol, hypertention. |
Johsen SP 2005 | Denmark | NCC | 254/254 | Ischemic stroke | ELISA | IgA, IgG | Diabetes, smoking, hypertension, cholesterol, BMI, alcohol intake, and education. |
Li FL 2004 | China | CSCC | 65/25 | Stroke | ELISA | IgA, IgG, IgM | None |
Anzini A 2004 | Italy | CSCC | 141/192 | Ischemic stroke | MIF | IgA, IgG, IgM | Age, gender, CV risk factors and socioeconomic status. |
Manuela V 2004 | Netherlands | CSCC | 41/55 | Ischemic stroke | ELISA | IgA, IgG | Smoking, hypertension and hypercholesterolemia. |
Apfalter P 2004 | Australia | CSCC | 45/30 | Stroke, TIA | MIF | IgA, IgG, IgM | None |
Carusone CS 2004 | Canada | CSCC | 28/24 | Stroke | MIF | IgA, IgG | Age, gender and smoking. |
Bucurescu G 2003 | USA | CSCC | 25/25 | Stroke, TIA | MIF | IgA, IgG | None |
Ngeh J 2003 | UK | CSCC | 100/87 | Stroke, TIA | ELISA | IgA, IgG, IgM | Age, gender, smoking, diabetes, hypertension, CHD. |
Kawamoto R 2003 | Japan | CSCC | 40/85 | Ischemic stroke | ELISA | IgG | None |
Sirmatel F 2003 | Turkey | CSCC | 26/53 | Ischemic stroke | MIF | IgG | None |
Zou R 2003 | China | CSCC | 112/50 | Stroke | ELISA | IgM, IgG | None |
Wolf SC 2003 | Germany | CSCC | 30/116 | Ischemic stroke | ELISA | IgA, IgG | Age, gender, diabetes, match for other risks factors. |
Sessa R 2003 | Italy | CSCC | 18/33 | Ischemic stroke,TIA | MIF | IgA, IgG | None |
Smiega M 2003 | Canada | NCC | 107/3061 | Stroke | MIF | IgA ,IgG | Age, gender, diabetes, smoking, hypertension, and hypercholesterolemia. |
Tanne D 2003 | Israel | NCC | 134/134 | Ischemic stroke | ELISA | IgA, IgG | Diabetes, smoking, BMI, hypertension. |
Katie A C 2003 | Australia | PC | 119/1493 | Stroke | MIF | IgA, IgG | Age, gender, diabetes, smoking, BMI, hypertension, cholesterol, TG, hemoglobin and systolic blood pressure. |
Gerdes v 2002 | Netherlands | NCC | 26/273 | Ischemic stroke | ELISA | IgA, IgG | None |
Madre JG 2002 | Spain | CSCC | 91/112 | Ischemic stroke | MIF | IgA | None |
Tarnacka B 2002 | Poland | CSCC | 20/15 | Sympotomatic carotid disease | ELISA | IgG | None |
LaBiche R 2001 | USA | CSCC | 36/55 | Sympotomatic carotid disease | MIF | IgA, IgG, IgM | None |
Katsenis C 2001 | Greece | CSCC | 20/15 | Sympotomatic carotid disease | ELISA | IgM | None |
Elkind MS 2000 | USA | CSCC | 89/89 | Ischemic stroke | MIF | IgA, IgG | Diabetes, smoking, hypertension, HDL, education, match for age, gender, race. |
Glader CA 1999 | Sweden | NCC | 97/197 | Ischemic stroke | MIF | IgA, IgG | Diabetes, smoking, BMI, hypertension, hypercholesterolmia. |
Wimmer MLJ 1996 | Germany | CSCC | 58/52 | Ischemic stroke,TIA | MIF | IgA, IgG | Age, gender, hypertension, migraine. |