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Table 2 Characteristic of studies using PCR or IHC

From: Chlamydia pneumoniae infection and cerebrovascular disease: a systematic review and meta-analysis

Author Y Country Study design Number of case/control Case assessment Detecting assay Specimen Odds ratio (95% CI)
Gagliardi RJ 2009 Brazil CSCC 52/59 Ischemic stroke, TIA PCR PBMC/DNA 0.37(0.01 ~ 9.32)
Kis Z 2007 Hungary CSCC 59/52 Ischemic stroke PCR PBMC/DNA 1.92(0.61 ~ 6.01)
Apfalter P 2004 Australia CSCC 45/30 Stroke, TIA PCR PBMC/DNA 0.65(0.09 ~ 4.89)
Wang SL 2003 China CSCC 93/90 Ischemic storke PCR PBMC/DNA 2.29(1.26 ~ 4.13)
Müller J 2003 Denmark CSCC 193/368 Stroke PCR PBMC/DNA 1.35(0.74 ~ 2.46)
Sessa R 2003 Italy CSCC 18/33 Ischemic stroke,TIA PCR PBMC/DNA 5.98(1.68 ~ 21.31)
Wohlschlaeger J 2005 German CSCC 9/23 Ischemic stroke PCR Carotid plaque/DNA 2.75(0.15 ~ 49.36)
Sessa R 2003 Italy CSCC 18/33 Ischemic stroke,TIA PCR Carotid plaque/DNA 1.84(0.56 ~ 6.05)
Katsenis C 2001 Greece CSCC 20/15 Sympotomatic carotid disease PCR Carotid plaque/DNA 4.19(0.19 ~ 93.97)
LaBiche R 2001 USA CSCC 37/57 Sympotomatic carotid disease PCR Carotid plaque/DNA 0.83(0.26 ~ 2.72)
Wohlschlaeger J 2005 German CSCC 9/23 Ischemic stroke IHC Carotid plaque 0.14(0.01 ~ 1.27)
Lastas A 2004 Lithuania CSCC 141/59 Sympotomatic carotid disease IHC Carotid plaque 0.88(0.33 ~ 2.38)
Neureiter D 2003 German CSCC 20/40 Ischemic stroke IHC Carotid plaque 9.0(2.32 ~ 34.88)
Jahromi BS 2003 Canada CSCC 57/13 Stoke,TIA IHC Carotid plaque 0.6(0.18 ~ 2.07)
  1. CSCC, cross-sectional case control; PCR, polymerase chain reaction; TIA, transient ischemic attack; IHC, immunohistochemical method; PBMC, peripherial blood mononuclear cell.