Table 3 Clinical and affective characteristics of SCA14 affected subjects and intrafamilial controls
Affected n = 9 | Intrafamilial controls n = 10 | |
|---|---|---|
Median/Mean (SD) | Median/Mean (SD) | |
SARA 1, at baseline | 5.50/5.83 (3.31) | 0 |
SARA 2, at three years follow up | 8.50/8.28 (3.62) | 0 |
Disease duration (in years) | 10.00/13.00 (8.60) | 0 |
Age at examination (in years) | 44.00/37.33 (14.17) | 43.5/41.9 (13.9) |
Disability stage 1, at baseline | 2.00/2.00 (0.50) | 0 |
Disability stage 2, at three years follow up | 2.00/2.00 (0.50) | 0 |
Mini-Mental State (MMS) | 30.00/29.67 (0.50) | 0 |
Education (in years) | 10/10.33 (2.2) | 10/10.8 (2.1) |
Male: Female | 7:2 | 4:6 |
Mean (n = 9) | Mean (n = 9)* | |
SCL-90 | ||
Total | 0.33 (0.41) | 0.38 (0.21) |
Somatization | 0.71 (0.80) | 0,67 (0.50) |
Obsessive-compulsive | 0,46 (0.69) | 0,70 (0.59) |
Interpersonal sensitivity | 0.42 (0.43) | 0.15 (0.16) |
Depression | 0.32 (0.48) | 0.48 (0.50) |
Anxiety | 0.20 (0.28) | 0.29 (0.25) |
Hostility | 0.28 (0.49) | 0.11 (0.12) |
Phobic anxiety | 0.25 (0.43) | 0.10 (0.14) |
Paranoid ideation | 0.22 (0.30) | 0.17 (0.19) |
Psychoticism | 0.09 (0.14) | 0.03 (0.05) |
Extra-scale | 0.50 (0.69) | 0.83 (0.51) |