Figure 1

Patient flow throughout the study in terms of seizure outcome. Terminal remission: seizure-freedom of at least 2 years preceding the end of follow-up. Pattern A (early and sustained seizure freedom): patients became seizure-free within 12 months of starting treatment and remained seizure-free. Pattern B (delayed and sustained seizure freedom): patients became seizure-free after 12 months of starting treatment and remained seizure-free. Pattern C (fluctuating course): patients fluctuating between periods of seizure freedom and relapse. Pattern D: patients never seizure-free for any complete year.