Figure 4

Correlations of sensory profile and nerve fiber density with pain-related evoked potential amplitudes. Scatter plots show correlations between PREP peak-to-peak-amplitudes (PPA) recoded after stimulation at the feet and QST parameters (warm detection threshold, WDT; cold detection threshold, CDT; thermal sensory limen, TSL; vibration detection threshold, VDT). a) PREP PPA correlated positively with CDT in male (correlation coefficient: 0.564, p = 0.002) and female Fabry patients (correlation coefficient: 0.340, p = 0.034). b) PREP PPA correlated positively with WDT only in male Fabry patients (correlation coefficient: 0.390, p = 0.04). c, d) TSL and VDT did not correlate with PREP PPA in either gender. e) Distal IEFND did not correlate with PREP PPA obtained after stimulation at the foot.