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Figure 2 | BMC Neurology

Figure 2

From: Nuclear entrapment and extracellular depletion of PCOLCE is associated with muscle degeneration in oculopharyngeal muscular dystrophy

Figure 2

Transverse cryosections of VL muscle biopsies from an OPMD patient over a 6 year interval. A) Biopsy taken at the time of first presentation in the clinic. B) Biopsy of the same muscle as in (A) taken 6 years later. Sections were stained with haematoxylin-eosin. Muscle fibrosis is evidenced by fat infiltration (F), vacuole with basophilic rim (arrowhead) and thickening of the ECM (arrows). Scale bar equals 100 μm.

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