|
Parameter
|
Patients (n =67)
|
Controls (n =21)
|
p
|
|---|
| |
CCSVI-
|
CCSVI+
|
CCSVI-
|
CCSVI+
| |
|---|
|
n (%)
|
59 (88.1)
|
8 (11.9)
|
21(100)
|
0 (0)
|
0.1*
|
|
Female/male (%)
|
49.2/50.8
|
50.0/50.0
|
33.3/66.7
|
0/0
|
ns*
|
|
Age at onset (years ± SD)
|
27.5 ± 7.2
|
29.1 ± 9.7
|
-
|
0.6#
|
|
Disease duration (years ± SD)
|
8.4 ± 5.9
|
14.4 ± 6.5
|
-
|
0.01#
|
|
Disease course, n (%)
| | |
-
|
0.12*
|
|
CIS
|
5 (8.5)
|
0
|
|
RR
|
38 (64.4)
|
3 (37.5)
|
|
CP
|
16 (27.1)
|
5 (62.5)
|
|
Total
|
59 (100)
|
8 (100)
|
|
MSSS (mean ± SD)
|
5.2 ± 2.2
|
7.4 ± 1.4
|
-
|
0.008#
|
|
EDSS (mean ± SD)
|
3.6 ± 2.0
|
5.85 ± 1.8
| |
0.007#
|
- CCSVI: chronic cerebrospinal venous insufficiency; CIS: clinically isolated syndrome; RR: relapsing-remitting; CP: chronic progressive (including secondary progressive and primary progressive); MSSS: Multiple Sclerosis Severity Score; EDSS: Expanded Disability Status Scale; * χ
2; # ANOVA; values represent the means ± SD; ns: non-significant.
