Variables | Phenytoin group N = 37 | Sodium valproate N = 17 | p value |
---|---|---|---|
Age;(years) | 40 (16–85) | 42 (16–76) | 0.852 |
Male gender (%) | 17 (45.95) | 10 (58.82) | 0.379 |
No preexisting condition, N (%) | 5 (13.51) | 3 (17.65) | 0.696 |
History of epilepsy (%) | 6 (16.22) | 7 (41.18) | 0.084 |
Antiepileptic drug withdrawal (%) | 4 (10.81) | 5 (29.41) | 0.121 |
Admitted to internal medicine ward (%) | 14 (37.84) | 6 (35.29) | 1.000 |
Generalized tonic clonic seizure type (%) | 37 (100) | 16 (94.12) | 0.315 |
Weight (kgs)* | 55.5 (40–75) | 50 (39–97.5) | 0.343 |
Time to start treatment (minutes) | 5 (5–90) | 10 (5–35) | 0.127 |
Independent status prior to SE, N (%) | 28 (75.68) | 17 (100) | 0.177 |
Laboratory findings | |||
Hematocrit, g/dL* | 31 (15.6-45.7) | 36.5 (26–49.4) | 0.273 |
Total white blood cells, cells/mm3* | 11610 (4100–29700) | 8965 (1100–14500) | 0.168 |
Blood sugar, mg/dL* | 127 (37–568) | 131 (73–251) | 0.926 |
Serum creatinine, md/dL* | 1 (0.5-6.1) | 0.9 (0.5-7) | 0.445 |
Serum calcium, md/dL* | 8.4 (5.3-10.2) | 8.2 (0.9-10.7) | 0.976 |
Serum albumin, g/dL* | 3.3 (1.2-7.4) | 4.0 (2.2-5.1) | 0.072 |
ALT, U/L* | 30 (5–375) | 18 (4–165) | 0.242 |
AST, U/L* | 56 (11–473) | 25.5 (0.3-2.2) | 0.115 |
Creatinine kinase, U/L* | 276 (54–1500) | 174.5 (44–500) | 0.396 |
Abnormal CT brain findings* | 17 (58.62) | 7 (53.85) | 1.000 |
Electroencephalogram, N* | 9 (24.32) | 5 (29.42) | 0.745 |