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Table 1 Baseline characteristics of status epilepticus (SE) patients treated with intravenous phenytoin or intravenous sodium valproate as the first-line treatment

From: The efficacy of intravenous sodium valproate and phenytoin as the first-line treatment in status epilepticus: a comparison study

Variables

Phenytoin group N = 37

Sodium valproate N = 17

p value

Age;(years)

40 (16–85)

42 (16–76)

0.852

Male gender (%)

17 (45.95)

10 (58.82)

0.379

No preexisting condition, N (%)

5 (13.51)

3 (17.65)

0.696

History of epilepsy (%)

6 (16.22)

7 (41.18)

0.084

Antiepileptic drug withdrawal (%)

4 (10.81)

5 (29.41)

0.121

Admitted to internal medicine ward (%)

14 (37.84)

6 (35.29)

1.000

Generalized tonic clonic seizure type (%)

37 (100)

16 (94.12)

0.315

Weight (kgs)*

55.5 (40–75)

50 (39–97.5)

0.343

Time to start treatment (minutes)

5 (5–90)

10 (5–35)

0.127

Independent status prior to SE, N (%)

28 (75.68)

17 (100)

0.177

Laboratory findings

   

Hematocrit, g/dL*

31 (15.6-45.7)

36.5 (26–49.4)

0.273

Total white blood cells, cells/mm3*

11610 (4100–29700)

8965 (1100–14500)

0.168

Blood sugar, mg/dL*

127 (37–568)

131 (73–251)

0.926

Serum creatinine, md/dL*

1 (0.5-6.1)

0.9 (0.5-7)

0.445

Serum calcium, md/dL*

8.4 (5.3-10.2)

8.2 (0.9-10.7)

0.976

Serum albumin, g/dL*

3.3 (1.2-7.4)

4.0 (2.2-5.1)

0.072

ALT, U/L*

30 (5–375)

18 (4–165)

0.242

AST, U/L*

56 (11–473)

25.5 (0.3-2.2)

0.115

Creatinine kinase, U/L*

276 (54–1500)

174.5 (44–500)

0.396

Abnormal CT brain findings*

17 (58.62)

7 (53.85)

1.000

Electroencephalogram, N*

9 (24.32)

5 (29.42)

0.745

  1. Note. Data presented as median (range) or number (percentage), Data in phenytoin or sodium valproate group may not equal to 37 or 17, respectively due to missing data, ALT serum alanine transaminase, AST serum aspartate transaminase, CT computed tomography, * indicates missing data.