Comparison of diffusion-weighted imaging and contrast-enhanced T1-weighted imaging on a single baseline MRI for demonstrating dissemination in time in multiple sclerosis

Table 1 Classification of the types and subtypes of demyelinating lesions

Lesion type	CE T1WI	DWI	Lesion subtype	DWI	ADC	eADC
I	C+	Hyper	A	Hyper	Hypo	Hyper
II	C+	Iso or hypo	A	Hyper	Hypo	Hyper
III	C–	Hyper	B	Iso, hypo or hyper (T2 T-S)	Iso or hyper	Iso or hypo
IV	C–	Iso or hypo

CE T1WI, contrast-enhanced T1-weighted imaging; DWI, diffusion-weighted imaging; ADC, apparent diffusion coefficient; eADC, exponential apparent diffusion coefficient; C +, enhancing; C –, nonenhancing; hyper, hyperintense; iso, isointense; hypo, hypointense; T2 T-S, T2-shine through effect.

ISSN: 1471-2377