Figure 1
From: Clinical baseline factors predict response to natalizumab: their usefulness in patient selection
Clinical course before and during natalizumab of three subjects is displayed. Pt = patient. BET is = 1 in the case of both patients 15 and 57: Patient 15 worsened by 2 EDSS points in the year prior to treatment, while in the year following treatment he/she worsened by less than one EDSS point. Patient 57 worsened by 0.5 EDSS point in the year prior to treatment, while in the year following treatment he/she improved by 1.5 EDSS point. In both cases, patients experienced a decrease by at least one point in the extent of worsening in EDSS during the year of treatment as compared to that in the year prior to treatment. In contrast, Patient 12 had stable disability throughout the before and after treatment periods.