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Table 3 Comparisons of the levels of neuroinflammatory factors in CSF among control, PD-NCI and PD-CI groups

From: Potential biomarkers relating pathological proteins, neuroinflammatory factors and free radicals in PD patients with cognitive impairment: a cross-sectional study

Neuroinflammatory factors

Control group (31 cases)

PD-NCI group (26 cases)

PD-CI group (36 cases)

P1

P2

P3

IL-6 (pg/ml)

1.414 ± 0.295

1.382 ± 0.307

1.716 ± 0.187

0.084

0.025

0.014

IL-1β (pg/ml)

17.078 (14.578 ~ 18.943)

19.522 (16.759 ~ 31.843)

19.625 (17.792 ~ 29.010)

0.050

0.000

0.870

TNF-α (pg/ml)

139.227 (78.938 ~ 168.261)

77.356 (34.580 ~ 180.960)

71.480 (36.467 ~ 147.145)

0.328

0.006

0.392

INF-Îł (pg/ml)

9.067 ± 2.496

6.695 ± 1.712

6.601 ± 2.049

0.027

0.003

0.935

PGE2 (pg/ml)

6.105 (5.564 ~ 8.960)

6.550 (5.589 ~ 13.771)

6.973 (4.977 ~ 16.392)

0.337

0.730

0.775

  1. P1: Control group vs. PD-NCI group; P2: Control group vs. PD-CI group, P3: PD-NCI group vs. PD-CI group.