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Table 4 Results of the univariate and multivariate Cox proportional hazard models for mortality

From: Clinical significance of cerebrovascular complications in patients with acute infective endocarditis: a retrospective analysis of a 12-year single-center experience

  Univariate Multivariate (model 1) Multivariate (model 2)
Variables HR (CI) P HR (CI) P HR (CI) P
Age ≥65 2.730 (1.297-5.748) 0.008 3.386 (1.563-7.335) 0.002 3.138 (1.421-6.930) 0.005
Male 1.534 (0.745-3.159) 0.245     
Diabetes mellitus 4.082 (1.975-8.435) <0.001     
Hypertension 2.805 (1.311-6.005) 0.008     
Atrial fibrillation 2.152 (1.049-4.415) 0.037     
History of CHF 2.773 (1.354-5.679) 0.005     
Comorbidity index >2 6.002 (2.902-12.414) <0.001     
Prosthetic valves 3.076 (1.438-6.578) 0.004    2.819 (1.315-6.044) 0.008
Mitral valve IE 2.189 (0.764-6.274) 0.145     
Aortic valve IE 0.719 (0.346-1.494) 0.377     
Dual valve IE 1.280 (0.570-2.875) 0.550     
Staphylococcus aureus 2.621 (1.166-5.891) 0.020     
No surgery 3.936 (1.895-8.177) <0.001     
Major CVC 2.931 (1.304-6.586) 0.009 3.786 (1.635-8.771) 0.002 3.893 (1.649-9.194) 0.002
  1. HR, hazard ratio; CI, 95% confidence interval; IE, infective endocarditis; CVC, cerebrovascular complication.