Table 2 Inflammatory parameters in controls and acute ischemic stroke patients measured within 6 hours (stroke 1) and one week after (stroke 2) the insult
From: Relevance of novel inflammatory markers in stroke-induced immunosuppression
Control (n = 14) | Stroke 1 (n = 12) | Stroke 2 (n = 12) | |
|---|---|---|---|
suPAR, ng/mL | 3.62 [3.30-4.91] | 5.04 [3.93-6.58]a | 4.64 [4.15-6.35]a |
CRP, mg/L | 2.37 [1.40-3.36] | 2.83 [1.98-4.15] | 11.48 [9.73-20.52]ab |
WBC, 109/L | 6.38 [5.35-8.58] | 7.42 [5.50-8.81] | 10.87 [7.85-13.90]ab |
Neutrophil, 109/L | 4.50 [3.54-5.49] | 5.97 [4.11-7.68] | 8.10 [5.82-11.75]ab |
CD64+/neutrophil, % | 5.95 [5.41-8.75] | 32.38 [9.21-43.93]a | 4.06 [1.73-6.77]ab |
CD64 MFI/neutrophil, au | 262 [145–505] | 331 [205–528] | 258 [93–838] |
CD177+/neutrophil, % | 53.24 [44.10-65.58] | 76.95 [47.18-89.68]a | 73.46 [44.55-84.28]a |
CD177 MFI/neutrophil, au | 3780 [2112–4859] | 5887 [4429–9455] | 6208 [3143–6899] |
CD64+ CD177+/neutrophil, % | 2.78 [1.71-3.79] | 21.30 [0.98-31.58] | 0.99 [0.80-1.79]ab |
Monocyte, 109/L | 0.40 [0.38-0.53] | 0.45 [0.33-0.68] | 0.50 [0.40-0.68] |
CD11b+/monocyte, % | 83.50 [68.30-89.03] | 84.55 [73.60-91.22] | 89.90 [76.08-94.03] |
CD64+/monocyte, % | 31.32 [14.65-56.20] | 22.51 [10.00-45.65] | 15.29 [5.80-36.34] |
CD64 MFI/monocyte, au | 280 [69–610] | 955 [223–1658] | 142 [42–365]b |
CD177+/monocyte, % | 26.09 [11.81-40.53] | 36.15 [23.83-61.22]a | 43.47 [30.52-67.97]a |
CD177 MFI/monocyte, au | 2293 [1378–3625] | 4705 [1774–6483] | 2492 [1479–3503] |
CD64+ CD177+/monocyte, % | 1.43 [0.65-2.36] | 2.50 [0.69-4.21] | 1.15 [0.77-1.94] |
Lymphocyte, 109/L | 1.49 [0.96-2.25] | 1.24 [0.70-1.50] | 1.34 [0.53-1.84] |
CD4+/lymphocyte, % | 35.41 [27.51-44.17] | 9.08 [3.85-23.96]a | 22.13 [18.41-41.86]b |
CD4+ CD25high/CD4+, % | 9.38 [7.52-13.95] | 10.46 [9.40-13.13] | 14.59 [8.97-18.25] |