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Table 3 Autozygosity mapping data generated by genotyping eight members of the two autosomal recessive spastic CP families. Subjects 4718, 4719, 4720 and 4722 represent family A; subjects 4578, 4579, 4581 and 4679 represent family B as demonstrated in Figure 2. This Table is organised according to the definitive marker order determined from current databases and the physical contig mapping undertaken. The minimum homozygous region is highlighted. *Denotes an unaffected family member.

From: Homozygosity for a missense mutation in the 67 kDa isoform of glutamate decarboxylase in a family with autosomal recessive spastic cerebral palsy: parallels with Stiff-Person Syndrome and other movement disorders

Marker Base position 4718 4719 4722* 4720* 4578 4579 4581 4679
D2S2157 AFMA119YH5 166029867 145 145 145/147 145 145/147 145/147 145/147 145/147
D2S124 AFM094ZC9 166347755 160 160 160 160 160/163 160/163 160/163 160/163
D2S2330 AFMC015YD9 166900134 156 156 156/158 156/158 160/168 160/168 160/168 160/168
CHLC.GATA71B02 167624503 240/256 240/256 240/256 240/256 240/256 240/256 240/256 240/256
D2S2345 AFM080XG9 168922932 156 156 150/156 150/156 152 152 152 152
CHLC.GATA71D01 169848018 193 193 193 193 193 193 193 193
D2S294 AFM205XF12 170579380 186 186 186 186 208 208 208 208
AFMA109YC1 171576976 256 256 254/256 256 254 254 254 254
D2S376 AFM319XG1 171576985 235 235 235 235 235 235 235 235
D2S2284 AFMB314YE1 171696071 166 166 166 166 166 166 166 166
D2S2177 AFMA155TF9 171790203 118 118 118 118 128 128 128 128
D2S2194 AFMA222XB9 171884139 141 141 141 141/143 145 145 145 145
D2S333 AFM2702E9 172592103 189 189 189/191 189/191 189 189 189 189
D2S2302 AFMB342ZD9 172758604 204 204 199/204 199/204 204 204 204 204
D2S2381 AFMA082TF5 172861090 222 222 226 222/226 224 224 224 224
D2S326 AFM266VE1 173299492 92 92 92 92 92 92 92 92
AFMA304WB1 176057526 130/132 122/132 130/132 122/132 124 124 124 124
D2S138 AFM176XD4 177947395 108 108 113 108/113 111/117 111 111 111
D2S148 AFM200WA11 178434054 184/188 184/188 184/194 184/194 188/190 186 186 186
D2S300 AFM214XC3 178826338 87/89 87/89 87/89 87/89 87/89 89 89 89