Table 3 Frequency of the THBD Ala455Val AA genotype in cases and controls (proportion with AA genotype in parentheses) as stratified by race and other stroke risk factors; with associated crude and adjusted odds ratios
Risk Factor | Percentage of cases with the AA genotype (proportion) | Percentage of Controls with the AA genotype (proportion) | Crude OR ^ (95% CI) | Adjusted OR*^ (95% CI) |
|---|---|---|---|---|
White | 79% (62/79) | 68% (93/137) | 1.7 (0.9–3.3) | 1.6 (0.8–3.2) |
Black | 87% (54/62) | 81% (59/73) | 1.8 (0.4–7.9) | 2.7 (0.9–8.0) |
Current smoking | 84% (54/64) | 71% (40/56) | 2.2 (0.9–5.3) | 3.0 (1.1–7.8) |
No current smoking | 81% (62/77) | 73% (112/154) | 1.6 (0.8–3.0) | 1.5 (0.7–2.9) |
Hypertension | 85% (33/39) | 61% (17/28) | 3.6 (1.1–11.3) | 5.7 (1.4–22.6) |
No hypertension | 81% (83/102) | 74% (135/182) | 1.5 (0.8–2.8) | 1.6 (0.8–3.0) |
Diabetes** | 84% (16/19) | 86% (6/7) | Not performed | Not performed |
No Diabetes | 82% (100/122) | 72% (146/203) | 1.8 (1.0–3.1) | 1.9 (1.1–3.4) |
Angina/MI ** | 86% (18/21) | 56% (5/9) | Not performed | Not performed |
No Angina/MI | 82% (98/120) | 73% (147/201) | 1.6 (0.9–2.9) | 1.7 (.95–3.1) |
Overall | 82% (116/141) | 72% (152/210) | 1.8 (1.1–3.0) | 1.9 (1.1–3.3) |