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Table 1 General characteristics of patients(mean ± standard deviation)

From: "Closing-in" phenomenon in Alzheimer's disease and subcortical vascular dementia

Groups

Younger controls (N = 30)

Elderly controls (N = 22)

Alzheimer's disease (N = 98)

Small Vessel Dementia (N = 48)

P-value*

Sex (M : F)

8:22

14 : 8

33 : 65

22 : 26

NS

Age

29.48 ± 5.90

67.30 ± 8.46

76.92 ± 8.03

76.75 ± 5.87

NS

Age of onset

-

-

73.27 ± 11.79

72.28 ± 12.61

NS

Duration

-

-

33.10 ± 23.10

26.30 ± 27.19

NS

Education

14.57 ± 0.98

10.43 ± 6.58

6.46 ± 5.47

6.96 ± 4.89

NS

MMSE

29.10 ± 1.21

28.12 ± 1.64

14.58 ± 5.67

16.58 ± 5.04

0.03

Barthel index

19.81 ± 0.21

19.11 ± 1.21

17.46 ± 4.53

11.26 ± 6.74

0.00

CDR

-

-

1.76 ± 0.76

1.77 ± 0.71

NS

GDS

-

-

16.37 ± 7.50

20.94 ± 4.97

0.04

  1. *Statistical significance was tested between Alzheimer disease and Vascular dementia MMSE; Mini-Mental State Examination GDS; Geriatric Depression Scale CDR; Clinical Dementia Rating Scale