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Table 1 Characteristics of AVM patients enrolled in a pilot clinical study to test effects of oral doxycycline treatment on MMP-9 in AVM lesions.

From: Suppression of MMP-9 by doxycycline in brain arteriovenous malformations

Group Age Gender S-M score* AVM size** Draining veins History of hemorrhage Number of embolization treatments
Dox 50 M 4 38 Superficial & Deep No 1
Dox 48 F 4 30 Deep Yes 0
Dox 52 M 4 42 Superficial & Deep Yes 2
Dox 43 M 3 29 Superficial & Deep No 1
Dox 23 M 4 34 Superficial & Deep No 2
Dox 28 M 4 40 Superficial Yes 2
Dox 56 M 2 10 Superficial No  
Dox 41 F 3 30 Superficial No 1
Dox 62 M 2 41 Superficial No 1
Dox 42 M 2 2 Superficial Yes 0
Placebo 53 M 2 28 Superficial & Deep No 1
Placebo 17 M 1 18 Superficial No 1
Placebo 48 F 2 13 Deep No 0
Placebo 22 M 3 19 Deep Yes 0
  1. * Spetzler-Martin score (15), **AVM maximum diameter (10). Dox = doxycycline