From: Effect of pre-stroke use of ACE inhibitors on ischemic stroke severity
Number of patients | ACEI group 33 (26%) | Non-ACEI group 93 (74%) | p-value |
---|---|---|---|
Sex (women/men) | 13/20 | 43/50 | |
• % women | 39% | 46% | 0.55 |
• % men | 61% | 54% | 0.55 |
Mean age (year) ± SD | 73 ± 11 | 70 ± 13 | 0.23 |
Risk factors: | |||
History of hypertension | 78% | 65% | 0.19 |
History of diabetes | 32% | 24% | 0.36 |
History of hyperlipidemia | 28% | 22% | 0.48 |
History of cardiac disease | 39% | 21% | 0.06 |
• CHF | 23% | 9% | 0.03* |
• AF | 10% | 7% | 0.69 |
• CAD | 6% | 5% | 0.98 |
History of smoking | 16% | 11% | 0.53 |
History of prior TIA | 10% | 16% | 0.39 |
Concomitant medications: | |||
Antiplatelets | 37% | 41% | 0.68 |
Anticoagulants | 12% | 10% | 0.74 |
Statins | 20% | 21% | 0.99 |
Other BP lowering agents | 56% | 52% | 0.84 |
• Diuretics | 25% | 18% | 0.45 |
• B-blockers | 18% | 27% | 0.35 |
• Ca++ blockers | 13% | 13% | 0.99 |
• ARB | 0% | 4% | 0.57 |
Time from stroke-to evaluation | |||
• 0–6 h | 61% | 63% | 0.83 |
• 6–25 h | 39% | 37% | 0.83 |
Clinical features: | |||
NIHSS score, median | 5.5 | 9 | 0.036* |
SBP (mean ± SD), mmHg | 162 ± 27 | 158 ± 31 | 0.35 |
DBP (mean ± SD), mmHg | 84 ± 16 | 81 ± 20 | 0.38 |
Temperature (mean ± SD), F° | 97 ± 7 | 98 ± 6 | 0.34 |