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Table 1 Comparison of demographic and clinical features between ACEI- and non ACEI-treated groups.

From: Effect of pre-stroke use of ACE inhibitors on ischemic stroke severity

Number of patients

ACEI group 33 (26%)

Non-ACEI group 93 (74%)

p-value

Sex (women/men)

13/20

43/50

 

   • % women

39%

46%

0.55

   • % men

61%

54%

0.55

Mean age (year) ± SD

73 ± 11

70 ± 13

0.23

Risk factors:

   

History of hypertension

78%

65%

0.19

History of diabetes

32%

24%

0.36

History of hyperlipidemia

28%

22%

0.48

History of cardiac disease

39%

21%

0.06

   • CHF

23%

9%

0.03*

   • AF

10%

7%

0.69

   • CAD

6%

5%

0.98

History of smoking

16%

11%

0.53

History of prior TIA

10%

16%

0.39

Concomitant medications:

   

Antiplatelets

37%

41%

0.68

Anticoagulants

12%

10%

0.74

Statins

20%

21%

0.99

Other BP lowering agents

56%

52%

0.84

   • Diuretics

25%

18%

0.45

   • B-blockers

18%

27%

0.35

   • Ca++ blockers

13%

13%

0.99

   • ARB

0%

4%

0.57

Time from stroke-to evaluation

   

   • 0–6 h

61%

63%

0.83

   • 6–25 h

39%

37%

0.83

Clinical features:

   

NIHSS score, median

5.5

9

0.036*

SBP (mean ± SD), mmHg

162 ± 27

158 ± 31

0.35

DBP (mean ± SD), mmHg

84 ± 16

81 ± 20

0.38

Temperature (mean ± SD), F°

97 ± 7

98 ± 6

0.34