Figure 1

Ideogram of the Chromosome 9p ALS-FTD locus. (A) ideogram of chromosome 9 showing the linked areas defined by Morita et al, Vance et al and Yan et al in 2006. The shared region flanked by D9S1678 and D9S2154 is shaded in grey. (B) Schematic representation of the known genes and predicted transcripts in the area shared by the Dutch, Scandinavian and North American families. In red, IFT74 where sequence variants associated with ALS-FTD, ALS and FTD were identified.