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Table 3 Regression Coefficients Expressing Cognitive Function Decrements (in SD units) for Each 10 Percentage Point Increment in 10-Year Risk of Stroke*

From: Framingham Stroke Risk Profile and poor cognitive function: a population-based study

  Unadjusted models Fully adjusted models†
Cognitive Domain β (95% CI) P β (95% CI) P
Time orientation -0.131 (-0.160 – -0.103) < 0.001 -0.022 (-0.058 – 0.014) 0.231
Immediate verbal memory -0.332 (-0.360 – -0.305) < 0.001 -0.037 (-0.073 – -0.001) 0.044
Delayed verbal memory -0.355 (-0.381 – -0.329) < 0.001 -0.064 (-0.097 – -0.032) < 0.001
Prospective memory -0.244 (-0.267 – -0.221) < 0.001 -0.026 (-0.059 – 0.007) 0.127
Semantic verbal fluency -0.276 (-0.300 – -0.252) < 0.001 -0.032 (-0.063 – -0.002) 0.038
Processing speed -0.185 (-0.212 – -0.157) < 0.001 -0.045 (-0.084 – -0.007) 0.022
Attention -0.167 (-0.194 – -0.141) < 0.001 -0.015 (-0.053 – 0.024) 0.449
Numeracy -0.181 (-0.206 – -0.157) < 0.001 -0.007 (-0.040 – 0.026) 0.683
  1. Pooled data are shown as sex-specific analyses gave similar results. Persons with a history of stroke or dementia were excluded.
  2. *Modified Framingham Stroke Risk Profile excluding left ventricular hypertrophy.
  3. †Adjusted for age, sex, testing interval, education, socioeconomic status, total net non-housing wealth, BMI, alcohol consumption, and depressive symptoms.