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Table 1 Characteristics of the different needles studied in the single- and multi-center trials of healthy volunteers

From: A novel needle for subcutaneous injection of interferon beta-1a: effect on pain in volunteers and satisfaction in patients with multiple sclerosis

Needle gauge

Number of bevels

Needle shield material

Type of silicone lubricant

Single-center study

Multi-center study

27a

3

Rubber

A

×

××

27

5

TPE

B

×

 

27

5

Rubber

A

×

 

27

5

TPE

A

×

×

27

3

Rubber

A

×

 

29

3

TPE

A

×

 

29

5

Rubber

A

×

 

29b

5

TPE

A

×

×

27 disposable needle

-

-

A

 

×

29 disposable needle

-

-

A

 

×

  1. IFN, interferon; sc, subcutaneous; tiw, three times weekly; TPE, Thermo Plastic Elastomer.
  2. aNeedle used previously for the injection of IFN β-1a, 44 or 22 mcg sc tiw.
  3. bNeedle used currently for the injection of IFN β-1a, 44 or 22 mcg sc tiw.
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BMC Neurology

ISSN: 1471-2377

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