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Table 4 Unadjusted and adjusted association between CRP and stroke severity (NIHSS, OCSP), stroke etiology (TOAST), outcomes (mRS, BI, mortality) and future vascular events in the 'Bergen stroke study' (n = 498)

From: Admission C – reactive protein after acute ischemic stroke is associated with stroke severity and mortality: The 'Bergen stroke study'

Subgroup

  

Unadjusted

Adjusted*

CRP categories:

  

3–9.9

10+

p

3–9.9

10+

p

NIHSS**

7–13

OR

1.77

3.17

0.01

1.85

3.28

0.02

 

14+

OR

1.11

1.89

 

1.03

1.85

 

OCSP (reference: LACI)

TACI

OR

0.84

1.79

0.008

0.87

1.61

0.03

 

PACI

OR

1.15

0.63

 

1.23

0.63

 
 

POCI

OR

0.64

1.07

 

0.74

1.21

 

TOAST (reference: Athero-thrombotic)

Cardioembolic

OR

0.90

1.89

0.04

0.93

2.03

0.09

 

Small vessel

OR

0.67

0.81

 

0.67

1.06

 
 

Other

OR

0.38

1.65

 

0.49

3.86

 
 

Unknown

OR

0.53

0.73

 

0.53

0.90

 

Poor outcome

(mRS >2)

 

OR

1.2

2.2

0.01

1.04

1.07

0.98

Poor outcome

(BI <95)

 

OR

1.26

2.08

0.03

1.02

1.18

0.88

Mortality

 

HR

2.20

5.49

1.20E-06

2.31

3.47

0.002

Future Vascular Events

 

HR

0.95

0.95

0.98

0.86

0.84

0.87

  1. NIHSS = National Institute of health Stroke Score
  2. OCSP = Oxford Community Stroke Project Classification
  3. TOAST = Trial of Org 10172 in Acute Stroke Treatment
  4. mRS = Modified Rankin scale
  5. BI = Barthel index
  6. HR = Hazards ratio from Cox regression
  7. OR = Hazards ratio from logistic regression
  8. *Adjusted for age, sex, NIHSS, pre-existing diabetes and intravenous thrombolysis in categories
  9. **Adjusted only for age and sex in categories