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Table 3 Disease characteristics of multifocal patients by symptoms and by signs at the CIS

From: MRI characteristics are predictive for CDMS in monofocal, but not in multifocal patients with a clinically isolated syndrome

  Multifocal Multifocal by symptoms Multifocal by signs p-value
N 222 122 100  
Sex – % of females 76% 77% 74% 0.6389
Age, median
(quartiles)
31
(25–37)
30.5
(25–36)
31
(25–38)
0.7919
Steroid treatment – % 70% 72% 67% 0.4632
EDSS (screening), median (quartiles) 2
1.5–2.5
2
1.5–2.5
2
1.5–2.5
0.9598
CSF positive of samples taken – % 118/138
86% (53%)
62/70
89% (51%)
56/68
82% (56%)
0.3405
Number of T2 lesions, median (quartiles) 21
(8–41)
19.5
(8–47)
22.5
(9–40)
0.9130
At least one Gd-enhancing lesion – % 42% 45% 39% 0.3376
At least one T1 hypointense lesion – % 73% 71% 74% 0.7627
  1. Fisher's exact test
  2. Mann-Whitney U-test
  3. EDSS: expanded disability status scale
  4. CSF: cerebrospinal fluid
  5. Gd: gadolinium