Skip to main content

Table 3 Disease characteristics of multifocal patients by symptoms and by signs at the CIS

From: MRI characteristics are predictive for CDMS in monofocal, but not in multifocal patients with a clinically isolated syndrome

 

Multifocal

Multifocal by symptoms

Multifocal by signs

p-value

N

222

122

100

 

Sex – % of females

76%

77%

74%

0.6389

Age, median

(quartiles)

31

(25–37)

30.5

(25–36)

31

(25–38)

0.7919

Steroid treatment – %

70%

72%

67%

0.4632

EDSS (screening), median (quartiles)

2

1.5–2.5

2

1.5–2.5

2

1.5–2.5

0.9598

CSF positive of samples taken – %

118/138

86% (53%)

62/70

89% (51%)

56/68

82% (56%)

0.3405

Number of T2 lesions, median (quartiles)

21

(8–41)

19.5

(8–47)

22.5

(9–40)

0.9130

At least one Gd-enhancing lesion – %

42%

45%

39%

0.3376

At least one T1 hypointense lesion – %

73%

71%

74%

0.7627

  1. Fisher's exact test
  2. Mann-Whitney U-test
  3. EDSS: expanded disability status scale
  4. CSF: cerebrospinal fluid
  5. Gd: gadolinium