From: Retrospective analysis of treatment outcome in 315 patients with oligodendroglial brain tumors
PCV n = 61 | PC n = 84 | ||||
---|---|---|---|---|---|
Age (in years) | < 50 | 40 | (66%) | 53 | (63%) |
≥50 | 21 | (34%) | 31 | (37%) | |
median (range) | 44 (14 – 73) | 42 (19 – 77) | |||
Sex | male | 38 | (62%) | 54 | (64%) |
female | 23 | (38%) | 30 | (36%) | |
Time from diagnosis of oligodendroglioma to onset of chemotherapy (in years) | median (range) | 2.8 (0 – 17) | 0.4 (0 – 18) | ||
Resection prior to chemo-therapy | yes | 30 | (49%) | 23 | (27%) |
no | 31 | (51%) | 61 | (73%) | |
Radiotherapy or seed implantation prior to chemotherapy | yes | 30 | (49%) | 54 | (64%) |
no | 31 | (51%) | 65 | (36%) | |
Histology and grade | Oligodendroglioma, WHO II | 10 | (16%) | 16 | (19%) |
Oligodendroglioma, WHO III | 6 | (10%) | 7 | (8%) | |
Oligoastrocytoma, WHO II | 22 | (36%) | 40 | (48%) | |
Oligoastrocytoma, WHO III | 21 | (34%) | 18 | (21%) | |
Other, WHO III/IV° | 2 | (3%) | 3 | (4%) | |
Karnofsky performance score | < 90 | 24 | (41%) | 28 | (34%) |
≥90 | 35 | (59%) | 55 | (66%) | |
Unknown | 2 | 1 |