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Figure 1 | BMC Neurology

Figure 1

From: An analysis of Methylenetetrahydrofolate reductase and Glutathione S-transferase omega-1 genes as modifiers of the cerebral response to ischemia

Figure 1

The metabolic pathways regulating oxidative stress. Abbreviations: MTHFR- Methylenetetrahydrofolate reductase, THF- tetrahydro folate, Hcy- Homocysteine, SAM- S-Adenosyl methionine, eNOS-endothelial nitric oxide synthase, iNOS-inducible nitric oxide synthase, ADMA- asymmetric dimethylarginine, NO- nitric oxide, O2 - – superoxide radical, ONOO- peroxinitrite, H2O2-hydrogen peroxide, NADPH – nicotinamide adenine dinucleotide phosphate, GSTO-1- Glutathione S-transferase omega-1, GSSG -glutathione disulfide, ROOH- reduced hydroperoxides, ROH- alcohol, H2O- water.

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