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Table 3 Baseline characteristics of the patients grouped according to the presence of Nabs

From: Neutralizing antibodies explain the poor clinical response to Interferon beta in a small proportion of patients with Multiple Sclerosis: a retrospective study

Characteristics

NAbs status

P

 

Negative

(n = 124)

Positive

(n = 17)

 

Gender

   

   Female

80 [64.5]

10 [58.8]

0.65

   Male

44 [35.5]

7 [41.2]

0.65

Age (years)

38 ± 9.4 (21-64)

43 ± 10.8 (31-67)

0.046

Disease duration (years)

11 ± 5.8 (2-29)

11 ± 7.4 (3-34)

0.92

Treatment duration (in years)

4 ± 2.2 (1-10)

4 ± 1.7 (1-7)

0.14

IFNβ type

  

0.96

   Avonex (n = 12)

11 [8.9]

1 [5.9]

 

   Betaferon (n = 36)

31 [25.0]

5 [29.4]

 

   Rebif 22 (n = 48)

42 [33.8]

6 [35.3]

 

   Rebif 44 (n = 45)

40 [32.3]

5 [29.4]

 
  1. Data are percentage [%] or mean ± SD (range)